Warner Bros.’ R-rated comedy stayed at No. 1 in its second outing at the box office.

Defying convention, Warner Bros.’ R-rated comedy “The Hangover” stayed at No. 1 in its second outing at the domestic box office, dipping a mere 26% an estimated $33.4 million from 3,355 theaters for a cume of $105.3 million in its first 10 days.

Disney-Pixar’s 3-D toon “Up” likewise continued to dazzle in its third weekend, declining 31% to an estimated $30.5 million from 3,886 runs. Pic’s cume is $187.2 million–the second-best domestic gross of any summer film save for Paramount’s “Star Trek.”

Third-man out was Sony’s new entry “Taking of Pelham 1 2 3.” Adult-skewing action-drama debuted at No. 2 in grossing a solid-to-strong $25 million from 3,074 theaters. Heading into the weekend, Sony knew “Pelham” had tough competition in “Hangover” and “Up.”

It was a rough weekend for Eddie Murphy, whose family pic “Imagine That” came in below expectations in grossing $5.7 million from 3,008 runs. The Paramount pic placed No. 6.

“Imagine” is Murphy’s first movie since last summer’s “Meet Dave,” which also misfired in opening to $5.4 million and cuming $11.8 million.

Estimated ticket sales for Friday through Sunday at U.S. and Canadian theatres, according to Hollywood.com. Final figures will be released Monday.

1. “The Hangover,” $33.4 million.

2. “Up,” $30.5 million.

3. “The Taking of Pelham 1 2 3,” $25 million.

4. “Night at the Museum: Battle of the Smithsonian,” $9.6 million.

5. “Land of the Lost,” $9.2 million.

6. “Imagine That,” $5.7 million.

7. “Star Trek,” $5.6 million.

8. “Terminator Salvation,” $4.7 million.

9. “Angels & Demons,” $4.2 million.

10. “Drag Me to Hell,” $3.9 million.

[Credit: Variety / Hollwood.com]